Failure to Appropriately Manage Warfarin Therapy and Elevated INR Results
Summary
The deficiency involves the facility’s failure to ensure a resident’s warfarin regimen was free from unnecessary drugs and appropriately managed in response to elevated INR values. The resident was admitted with a diagnosis including a prosthetic heart valve and was prescribed warfarin 5 mg with PT/INR monitoring. On one occasion, PT/INR labs drawn were noted as invalid, and subsequent PT/INR results showed markedly elevated values, including a prothrombin time of 94.9 seconds with an INR of 9.12, and later a prothrombin time of 180 seconds with an INR of 17.63. Despite these elevated results, the clinical record shows that warfarin 5 mg was administered on multiple days, including a day when the INR was documented as 9.12, and there is no evidence that the physician was contacted prior to administering warfarin in the presence of these elevated INRs. The record further shows inconsistencies between physician orders to hold warfarin and the medication administration record. The physician ordered warfarin 5 mg every other day beginning on a specified date, with PT/INR monitoring, and then ordered warfarin to be held pending PT/INR results. After PT/INR results were received, the physician adjusted the dose to 2.5 mg on one day and then to resume 5 mg daily on subsequent days. However, the MAR reflects that warfarin 2.5 mg was administered on the day ordered and warfarin 5 mg was administered on several days, even though the physician orders indicate warfarin 5 mg was to be on hold during some of those dates. Nursing documentation also shows that warfarin was administered when the INR was 3.38 and again when the INR was 9.12, without documented evidence of physician notification or guidance before administration. When the INR was later noted as critically elevated at 17.63, the physician was contacted and ordered vitamin K and daily PT/INR labs for two days. The record review revealed that these ordered PT/INR labs were not drawn on the specified days and were not completed until a later date. There is no evidence that staff followed up with the lab to ensure the ordered tests were performed as prescribed. By the time the labs were completed, the resident had experienced a change in condition, described as lethargic, nonresponsive, and not eating, and required further evaluation and eventual transfer to the hospital. The DON confirmed in interview that the labs were not drawn as ordered on the two days, that there was no evidence nurses contacted the physician before administering warfarin when the INR was elevated, and that the nurse who administered warfarin with an INR of 9.12 and other involved nurses were no longer available or no longer worked at the facility.
Penalty
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