Omitted Aspirin Order Led to Bilateral Lower-Leg DVTs
Summary
The facility failed to ensure that a resident was free from a significant medication error when Aspirin 81 mg ordered twice daily was not administered from the p.m. dose on 12/19/25 through the p.m. dose on 1/18/26. The resident had been admitted after hospitalization for surgical repair of a fractured left hip and had diagnoses including hypertension and COPD. Her BIMS score was 12, indicating moderate cognitive impairment. The medication was intended to continue for 30 days after admission, but the pharmacy-initiated order system entered an incorrect end date for the twice-daily Aspirin order, which caused a discontinued medication message in the EMR and prevented the corrected order from reappearing for administration. During the period when the Aspirin was omitted, the resident developed increasing lower-extremity symptoms documented in progress notes and therapy notes. She began reporting increased swelling in her left lower leg, then pain in both lower legs, significant bilateral lower-extremity swelling, difficulty bearing weight, and worsening weakness and pain that limited transfers, standing, walking, balance, and bed mobility. Nursing notes also documented purple bruising on the right leg, a dark bruise on the left lower leg, and 3+ pitting edema in the right lower extremity. Therapy staff noted a hematoma to the left medial gastrocnemius and a positive Homans' sign in the left lower leg, prompting notification of nursing leadership and a request for a Doppler exam. The Doppler exam completed on 12/31/25 showed bilateral DVTs in both lower legs, and the resident was started on Eliquis. A consultant pharmacist later identified that the Aspirin had not been administered since the last dose on 12/19/25 and had not been continued as ordered. Interviews with facility leadership and therapy staff confirmed that the pharmacy order entry error resulted in the resident not receiving the scheduled Aspirin for approximately two weeks and that the resident experienced increased pain, spontaneous bruising, and increased swelling in her lower legs before the DVTs were discovered.
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