Failure to Monitor Valproic Acid Levels and Notify MD/RP of Lab Refusals
Summary
The facility failed to ensure appropriate monitoring and follow-up for a resident receiving valproic acid for mood stabilization related to bipolar disorder. The resident had diagnoses including cerebral infarction, dementia, depression, and bipolar disorder, and was observed in bed appearing confused and intermittently mumbling, though able to state his name and not appearing sleepy, drowsy, or sedated. The resident’s MDS indicated severe cognitive impairment, and staff described him as alert but very confused, with behaviors including combativeness, hitting, spitting, and refusing care and laboratory draws. The resident had an active order for valproic acid delayed-release sprinkle capsules, 125 mg, given twice daily, and the MAR showed the medication was administered from December 2025 through the review date. The record did not contain a documented valproic acid level after initiation of therapy, and the RNS stated that a valproic acid level should have been obtained when the medication was started. The RNS also stated that monitoring valproic acid levels was important to assess therapeutic range and potential toxicity, and that the resident had been receiving valproic acid since 12/4/25. The record showed progress notes on 3/11/26 and 3/18/26 documenting refusals of lab draws as the third refusal for lab testing, but the documentation did not indicate whether the blood draws were attempted or whether the refusals occurred before an attempt. The RNS stated that if there was no documentation showing the MD and RP were notified, then notification did not occur, and the care plan intervention to notify the MD and RP with each refusal was not followed. The March MRR recommended obtaining valproic acid and ammonia levels, but the resident refused the lab draw on the expected date, and there was no documentation that the MD or RP were notified of the refusal.
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