Failure to Monitor Lithium Levels Leads to Toxicity
Summary
The facility failed to ensure that Resident #1's drug regimen was free from unnecessary drugs, specifically lithium, which was administered at an excessive dose and for an excessive duration without adequate monitoring. Resident #1, a male with a history of anxiety disorder, depression, schizophrenia, elevated blood pressure, and type 2 diabetes mellitus, was admitted to the facility and prescribed lithium carbonate. Despite the prescription, there was no order to monitor lithium levels routinely, leading to a critical lithium level of 5.3 mmol/L when Resident #1 was admitted to the hospital with acute toxic encephalopathy secondary to lithium toxicity. The facility's records revealed that Resident #1 received lithium carbonate 55 times out of 55 opportunities between the dates of 06/01/23 through 06/30/23. However, there was no documentation of routine lithium level monitoring. On 06/30/23, Resident #1's lithium level was found to be critically high at 4.5 mmol/L, and he was subsequently sent to the hospital where his lithium level was recorded at 5.3 mmol/L. The hospital diagnosed him with acute on chronic kidney disease and acute toxic encephalopathy due to lithium toxicity. Interviews with the facility's staff, including the NP, Pharmacy Consultant, MD, and DON, revealed a lack of clarity and responsibility regarding the monitoring of lithium levels. The NP and Pharmacy Consultant acknowledged the necessity of routine monitoring to prevent toxicity but failed to implement it. The MD and DON also expressed expectations for monitoring but did not ensure it was carried out. This lack of monitoring and communication among the staff led to Resident #1's severe lithium toxicity and subsequent hospitalization.
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