F0760

J

Significant Morphine Dosing Error Due to Misinterpretation of mg and mL

Dover, Delaware Survey Completed on 01-27-2026

Penalty

No penalty information released

Summary

The deficiency involves the facility’s failure to ensure a resident was free from significant medication errors when an incorrect dose of concentrated morphine sulfate oral solution was administered. The resident had dementia and a quarterly MDS showing moderately impaired cognition with a BIMS score of 10 and was receiving opioids for pain. The physician’s order in place directed that the resident receive 0.25 mL (5 mg) of morphine sulfate concentrate oral solution every three hours as needed for pain, and on a later date a new order was entered for MS Contin (morphine sulfate) 15 mg extended-release tablets by mouth twice daily for pain.

On the morning of the incident, the assigned LPN administered 15 mL of the concentrated morphine sulfate solution instead of the ordered 0.25 mL dose. In a written statement, the LPN reported that the electronic system displayed an ordered dose of morphine 15 mg, while the bottle label stated 0.25 mL, and that after seeking clarification from a supervisor, she was told to follow the dose listed in the MAR. The LPN then incorrectly interpreted 15 mg as 15 mL and administered that amount. Another nurse later confirmed that she had previously worked with the resident, was familiar with the correct 0.25 mL PRN dose, and had left 17.25 mL of morphine sulfate concentrate in the bottle at the end of her prior shift, while the LPN reported having given 15 mL to the resident.

The error was discovered during shift exchange when the outgoing nurse recognized the discrepancy between milligrams and milliliters. Nursing notes documented that the resident had received 15 mL of liquid morphine, and the medical director’s note confirmed that, given the concentration of 20 mg/mL, the resident received 300 mg instead of the prescribed 5 mg. The facility determined that the nurse failed to perform the rights of medication administration when she misinterpreted 15 mg as 15 mL, resulting in the resident receiving 59 times the ordered dose of morphine sulfate solution. The resident required administration of naloxone intramuscularly on two occasions to reverse the overdosage, and the situation was identified by surveyors as immediate jeopardy, past non-compliance.

Removal Plan

• Upon discovery of the medication error, R5 was immediately assessed and the physician was notified; a new order for Narcan (Naloxone) was obtained and administered; R5's responsible party and Hospice were notified; R5 was placed on alert charting to monitor vital signs and respiratory status.
• An audit was completed on residents with orders for liquid morphine and no other errors were identified.
• An audit of residents receiving controlled substances was completed to determine if any other residents had orders for the same medication in two different forms and no other residents were identified.
• The facility conducted a root cause analysis.
• Education with licensed nurses was completed on the five rights of medication administration.
• The medication error was reviewed with the medical director at an ad hoc QAPI meeting.
• The Director of Nursing will conduct audits of liquid morphine medication administration weekly until 100% compliance is achieved for 3 consecutive weeks, then monthly until 100% compliance is achieved for 3 consecutive months; all audits will be reviewed by the QAPI Committee.